Integrins

Introduction Integrins are a large family of homologous transmembrane linker proteins that include collagen, fibronectin and laminin. They are a family of cell-surface proteins that mediated cell adhesion, a process that is essential for anchorage, and act as cues for cell migration and signals for growth and differentaition.1 In addition to their biological importance to fundamental cellular processes, integrins play a part in immune function, tissue repair, tumour invasion, and platelet aggregation.2 The integrins are …showed first 75 words of 2361 total…

…showed last 75 words of 2361 total…R.M., Kopf G.S. Characterization of the binding of recombinant mouse sperm fertilin a subunit to mouse eggs: evidence for function as a cell adhesion molecule in sperm-egg binding. Develop. Biology, 187, 94-106 (1997) 11. Alon R., Kassner P., Carr M., Finger E.B., Hemler M.A., Springer T.A. Lymphocyte VLA-4 can mediate cell tethering, rolling and firm adhesions on VCAM-1 under flow. Cell. Biology. 128, 1243-1253. (1995) 12. Lodish., Berk., Zipursky., Matsudaira., Baltimore., Darnell. Molecular Cell Biology. 22, 968-1002